The carefully calibrated Exceptional Chronobiology Sleep Mask Refill by Noble Panacea is a weekly overnight treatment that visibly renews, replenishes and refreshes the skin. Developed with the circadian rhythm in mind, the creamy mask stars the brand’s OSMV™ Technology, a molecular vessel that releases high concentration actives sequentially for optimal visible results. The actives being delivered include polyhydroxy acid, a gentle exfoliator and antioxidant that promotes an even-looking skin tone, alongside retinol, a skin-smoothing form of vitamin A with plumping and brightening benefits. Fortifying the formula is a blend of peptides, ceramides and a trio of pre, pro and postbiotics, working in unison to protect and firm the appearance of the skin, while multi-weighted hyaluronic acid encourages the illusion of enhanced elasticity and bounce when you wake. After 4 Weeks: 100% felt skin looked replenished, energised, and healthy-looking 97% said skin felt firm and plumped 94% felt that stressed skin was soothed, with redness and irritation visibly reduced After 8 Weeks: 97% said skin looked luminous and radiant 91% said dark spots and pigmentation appear diminished and lightened 89% felt the appearance of deep wrinkles were improved Clinical trials tested on 35 women.